More than 10,000 Islamic State fighters have been killed since an international coalition began a campaign against the group in Iraq and Syria, the US says.
Deputy Secretary of State Antony Blinken told France Inter radio the coalition had seen “a lot of losses” within IS in the past nine months.
“It will end up having an impact,” he added, but warned IS remained resilient and capable of taking the initiative.
He spoke after the coalition met in Paris to discuss its strategy in Iraq.
Representatives backed Iraqi Prime Minister Haider al-Abadi’s plan to retake the city of Ramadi, whose capture by IS last month he described as a “failure” for the international community.
They also called for the “speedy launch” of efforts to end the conflict in Syria.


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